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  Dr. Aalim Weljie  
     
 

Position:

Adjunct Assistant Professor

Qualifications:

Ph.D. 2003. University of Calgary
BSc. 1996 Mount Allison University


Room:

BI 295/297

Phone:

403-220-5386

Email:

aweljie@ucalgary.ca

Web: http://people.ucalgary.ca/~aweljie/public/Home.html
 
     
 

Research Interests

The focus of my research interests are in the application of quantitative metabolic profiling methods to problems of environmental and medical importance. These methods, often referred to as 'metabolomics' techniques use analytical platforms such as NMR or mass spectrometry-based instrumentation (GC-MS, LC-MS) to evaluate levels of small molecule metabolites in biofluids and/or tissues.

 
     
 

Graduate Students

Name

Degree

Topic
Dang, Ngoc Ha Thi M.Sc.  
Sarfaraz, Mohammad Omair M.Sc.  

 
     
 

Selected publications

  • Takeda I, Stretch C, Barnaby P, Bhatnager K, Rankin K, Fu H, Weljie A, Jha N, Slupsky C. (2009) "Understanding the human salivary metabolome." NMR Biomed. (In Press, Mar 03, PMID: 19259987)
  • Dowlatabadi R, Weljie AM, Thorpe TA, Yeung EC, Vogel HJ. (2009) “Metabolic footprinting study of white spruce somatic embryogenesis using NMR spectroscopy” Plant Physiol. Biochem. 47:343-50.
  • Tremaroli V, Workentine ML, Weljie AM, Vogel HJ, Ceri H, Viti C, Tatti E, Zhang P, Hynes AP, Turner RJ, Zannoni D. (2009) “Metabolomic investigation of the bacterial response to a metal challenge.” Appl. Environ. Microbiol. 75:719-28
  • Shaykhutdinov RA, MacInnis GD, Weljie AM and Vogel, HJ “The Quantitative Analysis of Metabolites Concentrations in Human Urine Samples Using 13C{1H} NMR Spectroscopy” Metabolomics (In Press; Online Feb 03)
  • Weljie AM*, Newton J, Jirik, FR, and Vogel HJ. (2008) “Evaluating Low-Intensity Unknown Signals in Quantitative Proton NMR Mixture Analysis” Anal. Chem. 80:8956-65.
  • Hagel JH, Weljie AM, Vogel HJ, Facchini PJ. (2008) “Quantitative 1H NMR metabolomics as a functional genomics platform to investigate alkaloid biosynthesis in opium poppy.” Plant Physiol. 147:1805-21
  • McGrath BM, McKay R, Dave S, Seres P, Weljie AM, Slupsky CM, Hanstock CC, Greenshaw AJ and Silverstone PH. (2008) “Acute dextro-amphetamine administration does not alter brain myo-inositol levels in humans and animals: MRS investigations at 3 and 18.8 T.” Neuroscience Research, 61:351-9
  • Shearer J, Duggan GE, Weljie AM, Hittel DS, Wasserman DH, Vogel HJ. (2008) “Metabolomic profiling of dietary-induced insulin resistance in the high fat fed c57bl/6j mouse.” Diabetes, Obesity and Metabolism. 10:950-8
  • Zulak, KG, Weljie AM, Vogel HJ, Facchini PJ. (2008) “Quantitative 1H-NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures.” BMC Genomics. 8:5.
  • Weljie AM, Dowlatabadi R, Miller JB, Vogel HJ and Jirik FR. (2007) "An inflammatory arthritis-associated metabolite biomarker pattern revealed by 1H NMR spectroscopy" J. Proteome Res. 6:3456-64.
  • Slupsky CM, Rankin KN, Wagner J, Fu H, Chang D, Weljie AM, Saude EJ, Lix B, Greiner R, Sykes BD, and Marrie TJ (2007) “Characterization of the metabolic pathways responsible for gender, diurnal and age differences in humans.” Anal. Chem. 79:6995-7004.
  • Chang D, Weljie AM and Newton J. (2007) "Leveraging Latent Information in NMR for Robust Predictive Models." Pac Symp Biocomp 12:115-26.
  • Wishart DS et al. (2007) “HMDB: the Human Metabolome Database.” Nucleic Acids Res. 35 (Database issue):D521-6.
  • Weljie AM, Newton J, Mercier P, Carlson E and Slupsky CM. (2006). "Targeted profiling: quantitative analysis of 1H NMR metabolomics data." Anal Chem 78:4430-42

 

 

 

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